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Bong Dal Hee (Lee Yo Won) is a first year resident doctor who strives to become a surgeon despite her heart problem. She works under Dr. Ahn Jong Geun (Lee Bum Soo), a cardiac specialist, and even though they don't get off to a good start, the two grow fond of each other as time goes by. Dr. Lee Geon Wook (Kim Min Joon) divorced his wife, Dr. Jo Moon Kyung (Oh Yoon Ah), after he found out that his 6-year-old son was actually fathered by another man before they married. He still has feelings for her, but feels betrayed and cheated. This medical drama portrays the lives of resident doctors, their ups and downs, depicting crisis in a hospital as well as politics among its management staff.

Mi-Ja (Ye Ji-Won) is a 32 years old spinster. She lives with her grandmother and her grandmother’s two sisters. There’s also a widowed uncle that lives in their home as well his never before married son. Mi-Ja’s chance for success finally arrives when she is hired as a voice-over artist for a Japanese horror movie that is being re-released in Korea. While working as a dubbing artist, she quickly falls in love with Hyun-Woo (Ji Hyun-Woo), the notoriously mean producer that is overseeing their project. While Ji-Hyun doesn’t give the slightest hint that he is even remotely interested in her, M-Jja still feels that there is a special type of chemistry that exists between them. Because of this, M-Jja decides to follow her instincts to find true love, even if it means making a total embarrassment out of herself. Making things more difficult for Mi-Ja is the fact that her former boyfriend and his new girlfriend also work at the same studio.

Five celebrities who are not that knowledgeable face the challenge of having to solve 10 problems in order to escape the rooftop.