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High school students Yeo-Jin (Kwak Ji-Min) and Jae-Young (Han Yeo-Reum) plan a trip to Europe together. Jae-Young begins to prostitute herself to save up the money. Her best friend Yeo-Jin manages her appointments and also acts as a lookout when she meets her clients. Eventually, Jae-Young believes herself as as someone like legendary Indian figure Vasumitra, who converted men to Buddhism through sexual encounters. One day, a police raid occurs and Jae-Young jumps out of a motel window. She is gravely injured. At the hospital Jae-Young asks Yeo-Jin to bring to the hospital one of her favorite clients. When Yeo-Jin tracks down the client he refuses to go to the hospital unless Yeo-Jin has sex with him. Yeo-Jin reluctantly agrees for her dying friend. When they get to the hospital Jae-Young has already passed away.Jae-Young then seeks out Yeo-Jin's past clients one by one. One day, Yeo-Jin's father (Lee Eol) spots Jae-Young walking with an older man. Yeo-Jin's father is a detective. He begins to Jae-Young ...

Adapted from the manga "-50kg no Cinderella" (－50kgのシンデレラ).

Foshan's famous physician Dou Sam has only one daughter, Dou Gaa Kei. Although she is intelligent and has a strong interest in Chinese medicine. On the day of her marriage to the mayor's son Chong Gai Zou, a serious epidemic breaks out. Many patients, including him, die after taking Dou Sam's medicine, prompting the pharmacy to be shut down. Experiencing such an abrupt change in her life, Dou Gaa Kei is left feeling hopeless. At this time, Ding Yat Yuen, a merchant suffering from a terminal illness, purchases the pharmacy's assets with the intention of reselling it for profit. To keep the pharmacy intact, Dou Gaa Kei offers to treat his illness in exchange of him to not sell any of the assets. Through his connections, she meets a retired imperial physician, who passes on his medical knowledge to her. Meanwhile, Chong Gai Zou's twin brother has returned home. Tsui Gwan Yeuk, the daughter of a military general, confesses her love for him, but he holds a crush on his former sister-in-law instead. However, Dou Gaa Kei and Ding Yat Yuen have already developed feelings for each other after overcoming many challenges together. Just as the pharmacy is reopened and everything seems to have settled down, Ding Yat Yuen's life begins counting down...