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Following in the same theme of dangerous discoveries, the "Pandora's box" for the new series will be a medical treatment invented to prevent suicides. Eguchi plays Suzuki, a neuroscience researcher in a wheelchair who develops the treatment out of his desire to counter Japan's high suicide rate. --Tokyograph

Vud was in love with Kompai (Kob) but didn't have the courage to confess his feelings so he became close to her sister, Rodsarin, hoping that he would have a chance with Kompai. But when he realized that Kompai was not interested in him at all, he became engaged to Rodsarin before leaving to study abroad, along with Rodsarin's friend, Thitha. Thitha and Vud ended up starting a relationship while studying abroad. Vud sent a letter to Rodsarin, telling her that he was ending their engagement. Rodsarin became heartbroken and passed away. Kompai vowed to get revenged for her sister. She used Panin (Chakrit) as her tool to get back at them. Kompai planned for Thitha to fall for Panin, with the intentions of never letting her being with him.