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Uno Meiko is the daughter of parents who run a western style restaurant in Tokyo. She marries and moves to Osaka with her husband. Meiko experiences cultural differences between Tokyo and Osaka, as she lives as a mother and wife in Osaka.

Jejoongwon is the first modern hospital in Korea established in the Joseon era in 1885. Baek Do Yang is a nobleman who gives up his status to enter its ranks. Hwang Jung is a butcher's son who becomes a physician, while Seok Ran enters Jejoongwon as an interpreter but takes on medical training to become a doctor.

This documentary captures the start of K-pop groups 2PM & 2AM during their training days. By the end of the training process, One Day had been reduced to an eleven-member group. The band was then split into four-member ballad group 2AM and seven-member hip-hop group 2PM.