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"Mars Research Institute" is a variety show that features science in an entertaining way. Through the various experiments, the show makes science fun and entertaining. Discover the amazing science behind familiar objects and concepts, and gain scientific knowledge in a the comfort of your own home. Wang Han is the host and president of the "Mars Research Institute". Under his leadership, the experimenters unite to overcome many difficulties and hardships to solve common problems that effect everyone in their daily lives.

Top National Security agent Joo Tae Joo who is rapidly rising up the ranks, dislikes all animals. In order to obtain his next promotion, he volunteers to take on a mission in which he has to protect a special Chinese panda named Ming Ming. At its welcoming ceremony, Ming Ming is kidnapped by an international terrorist organization. While chasing after the terrorists, Tae Joo injures his head and is knocked out. When he finally regains consciousness, he finds out that he now possesses a strange ability to talk to the animals and finds a sole witness to the kidnapping incident – a stubborn retired military dog named Ali. Wanting to retake the title as the top agent, Tae Joo and Ali become unlikely partners on a mission to rescue Ming Ming.