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20-years-old Cho-Won (Cho Seung-Woo) is young man with autism. He lives with his highly protective mother Kyung-Sook (Kim Mi-Sook) and younger brother (Baek Sung-Hyun), who sometimes resents the attention his older brother receives from his mother. Through special schooling and taking part in physical activities, Cho-Won has adjusted relatively well into society. Cho-Won also seems to have a knack for running. After placing third in a race, his mother decides to hire a proper coach to train her son. Cho-Won then decides to take part in a marathon. Cho-Won hopes to break the marathon's fastest record of three hours.

The old-timer Bae Tae Shik butt heads with Han Jin Woo acting as the genius medical examiner. The two always differ in opinion, but whenever a case needs to be solved they respect each other’s strengths and act as an unbeatable duo.