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The leading lady is from a rich family and is currently in an arranged marriage. She finds and meets Mario and falls in love with him. Their stuggles as a couple starts because Mario is from a poor family.

Jejoongwon is the first modern hospital in Korea established in the Joseon era in 1885. Baek Do Yang is a nobleman who gives up his status to enter its ranks. Hwang Jung is a butcher's son who becomes a physician, while Seok Ran enters Jejoongwon as an interpreter but takes on medical training to become a doctor.

Story of Kadakkal Chandran, the Chief Minister of Kerala whose uncompromising attitude towards corruption and his dictatorial actions has gained him a lot of enemies. The events gets more intense when he faces an allegation.